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Vol 27. nos. 2&3.
June-September 2022

Immune regulation of AP-N, DDP4 and ACE2 receptors and the susceptibility to infections with coronavirus 229E, MERS-CoV and SARS-CoV2 (summary)
Izabela Gulbas, Maciej Chałubiński
Histamine intolerance belongs to biogenic intolerances. It is a form of adverse reaction to food. Key in the intolerance of biogenic amines is the lack of participation of immunomechanisms. Although the exact pathogenetic mechanism of histamine intolerance is still unclear. The reduced intestinal activity of diaminic oxidase, which plays a role in the degradation of histamine supplied with food, is assumed to be crucial. Measuring the level of histamine or DAO in the patient’s blood serum is currently possible, although according to some authors controversial. It is usually not recommended in the initial stages of routine diagnosis of food intolerances. However, in some patients, it can help in establishing the correct diagnosis. The purpose of the low-histamine diet is to enable the patient’s recovery and reduce symptoms from the digestive system. At the same time, it is crucial that the diet is full-fledged and acceptable to the patient. The article is focused on the dietary aspects of histamine intolerance. It discusses its sources in the diet, as well as the basics of low-histamine diet.

Keywords: histamine intolerance, pseudo-allergy, diet, biogenic amine
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